Is Tirzepatide a GLP-3? The Triple Agonist Mechanism Explained

Understanding how Tirzepatide's receptor targets produce its therapeutic effects.

Tirzepatide's Drug Class: What It Means

Tirzepatide is a once-weekly injectable that simultaneously activates GIP and GLP-1 receptors. GLP-1 activation suppresses appetite, slows gastric emptying, and enhances insulin secretion. GIP activation amplifies insulin response and may improve lipid metabolism and fat storage patterns. The dual mechanism produces greater weight loss than GLP-1-only drugs like semaglutide.

Frequently Asked Questions

What drug class is Tirzepatide?

Tirzepatide is a GIP/GLP-1 Dual Receptor Agonist. Tirzepatide is a once-weekly injectable that simultaneously activates GIP and GLP-1 receptors. GLP-1 activation suppresses appetite, slows gastric emptying, and enhances insulin secretion. GIP activation amplifies insulin response and may improve lipid metabolism and fat storage patterns. The dual mechanism produces greater weight loss than GLP-1-only drugs like semaglutide.

How does Tirzepatide work for weight loss?

Tirzepatide causes weight loss through its receptor activity. Tirzepatide is a once-weekly injectable that simultaneously activates GIP and GLP-1 receptors. GLP-1 activation suppresses appetite, slows gastric emptying, and enhances insulin secretion. GIP activation amplifies insulin response and may improve lipid metabolism and fat storage patterns. The dual mechanism produces greater weight loss than GLP-1-only drugs like semaglutide.

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Medical Disclaimer: Mechanism of action information is based on peer-reviewed pharmacological research and published clinical trial data. This content is educational and does not constitute medical advice.

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