Semaglutide Clinical Trials: Results & How to Enroll

Complete guide to Semaglutide clinical trial history, published results, and current research status.

Clinical Trial History

Phase 3 (STEP 1)
Weight reduction in adults with obesity

Semaglutide 2.4mg produced 14.9% mean weight loss vs 2.4% for placebo over 68 weeks.

Source: NEJM 2021; STEP 1 Trial
Phase 3 (SELECT)
Cardiovascular outcomes in overweight/obese patients

Semaglutide reduced major cardiovascular events (MACE) by 20% vs placebo in patients with established cardiovascular disease — a landmark finding leading to expanded use.

Source: NEJM 2023; SELECT Trial

Frequently Asked Questions

What clinical trials have studied Semaglutide?

Semaglutide has been studied in multiple clinical trials. The key findings are documented in the clinical research section of this guide. Refer to ClinicalTrials.gov for complete trial records and enrollment information.

Is Semaglutide still in clinical trials?

FDA approved for T2D (Ozempic, 2017), obesity (Wegovy, 2021), CV risk reduction (2023), oral T2D (Rybelsus, 2019). For current trial status, search ClinicalTrials.gov using the drug name "Semaglutide".

Exploring Retatrutide Access?

See how patients are accessing retatrutide through physician-supervised telehealth and compounding pharmacies.

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Medical Disclaimer: Clinical trial information is based on publicly available data from ClinicalTrials.gov and published research. This content does not constitute medical advice.

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